Inhibition of hepatitis C virus-like particle binding to target cells by antiviral antibodies in acute and chronic hepatitis C.

Title:

Inhibition of hepatitis C virus-like particle binding to target cells by antiviral antibodies in acute and chronic hepatitis C.

identifier:	4754
description:	epitope description:SQKIQLVNTNGSWHI antigen name:Genome polyprotein host organism:Homo sapiens antibody name:anti-HCV+ serum
aggregation:	instance of dataset
availability:	available
primaryPublications:	15308699

study type:	b cell assays
subject species:	Hepatitis C virus (isolate H77)

fullName:	Daniel Steinmann Heidi Barth Bettina Gissler Peter Schü rmann Mohammed I Adah J Tilman Gerlach Gerd R Pape Erik Depla Dirk Jacobs Geert Maertens Arvind H Patel Geneviè ve Inchauspé T Jake Liang Hubert E Blum Thomas F Baumert

method:	flow cytometry

name:	Inhibition of hepatitis C virus-like particle binding to target cells by antiviral antibodies in acute and chronic hepatitis C.
description:	HCV + serum with marked inhibition of binding activity of HCV-like particles (HCV-LPs) was preincubated with overlapping 15-mer peptides encompassing the entire envelope glycoprotein from the HCV-J strain. Only this peptide competed binding.

name:	iedb
homePage:	http://www.iedb.org

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