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Title: N-terminus of M2 protein could induce antibodies with inhibitory activity against influenza virus replication.
identifier: 8133
description:
epitope description:SLLTEVETPIR
antigen name:Matrix protein 2
host organism:Oryctolagus cuniculus
aggregation:
instance of dataset
availability:
available
primaryPublications: 12628550
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/780
landingPage: http://www.iedb.org/assay/8133
type:
Literature
publicationVenue:
FEMS Immunol Med Microbiol
dates:
2003
study type: b cell assays
subject species: Influenza A virus
fullName:
Wanli Liu
Hua Li
Ying-Hua Chen
method:
biological activity
name:
N-terminus of M2 protein could induce antibodies with inhibitory activity against influenza virus replication.
description:
The assay measured the inhibitory effect of antibodies against influenza viruses A and B replication in vitro by the Madin-Darby canine kidney cytopathic effect inhibitory assay. A similar inhibitory effect was shown against the influenza B virus B/wuhan/321/99 strain. The first eight residues of this epitope were found to be highly conserved among all 188 influenza A virus strains with available M2 protein amino acid sequences.

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