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identifier: 9370
description:
epitope description:EHKYSWKS
host organism:Mus musculus
antibody name:15F3-1
aggregation:
instance of dataset
availability:
available
primaryPublications: 11230414
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/857
landingPage: http://www.iedb.org/assay/9370
type:
Literature
publicationVenue:
J Clin Microbiol
dates:
2001
study type: b cell assays
subject species:
fullName:
H C Wu
Y L Huang
T T Chao
J T Jan
J L Huang
H Y Chiang
C C King
M F Shaio
method:
cross blocking
name:
Identification of B-cell epitope of dengue virus type 1 and its application in diagnosis of patients.
description:
This epitope was identified using a serotype-specific monoclonal antibody of dengue virus type 1 through a phage display library. It mimicks the sequence HKYSWK, which corresponds to amino acids 111 to 116 of the nonstructural protein of dengue virus type 1.
Binding of the monoclonal antibody, 15F3-1, to a phage clone was shown to be inhibited by the peptide P14M.

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