Mapping of a dengue virus neutralizing epitope critical for the infectivity of all serotypes: insight into the neutralization mechanism.

Title:

Mapping of a dengue virus neutralizing epitope critical for the infectivity of all serotypes: insight into the neutralization mechanism.

identifier:	10504
description:	epitope description:FKLEKEVAE antigen name:Genome polyprotein host organism:Mus musculus antibody name:4E11
aggregation:	instance of dataset
availability:	available
primaryPublications:	11457994

study type:	b cell assays
subject species:	Dengue virus 1 Nauru/West Pac/1974

fullName:	P Thullier C Demangel H Bedouelle F Mé gret A Jouan V Deubel J C Mazié P Lafaye

method:	ELISA

name:	Mapping of a dengue virus neutralizing epitope critical for the infectivity of all serotypes: insight into the neutralization mechanism.
description:	The monoclonal antibody 4E11 was shown to specifically bind a peptide corresponding to the epitope in direct ELISA, and the epitope was able to compete the mAb binding to immobilized envelope protein, showing high affinity.

name:	iedb
homePage:	http://www.iedb.org

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