Highly glycosylated human salivary molecules present oligosaccharides that mediate adhesion of leukocytes and Helicobacter pylori.

Title:

Highly glycosylated human salivary molecules present oligosaccharides that mediate adhesion of leukocytes and Helicobacter pylori.

identifier:	14802
description:	epitope description:alpha-L-Fucp-(1->2)-beta-D-Galp-(1->3)-[alpha-L-Fucp-(1->4)]-D-GlcNAc antigen name:Mucin-5B host organism:Mus musculus antibody name:anti-Le^b
aggregation:	instance of dataset
availability:	available
primaryPublications:	15697247

study type:	b cell assays
subject species:	Homo sapiens

fullName:	Akraporn Prakobphol Thomas Boré n Wenge Ma Peng Zhixiang Susan J Fisher

method:	western blot

name:	Highly glycosylated human salivary molecules present oligosaccharides that mediate adhesion of leukocytes and Helicobacter pylori.
description:	The sialyl Lewis X tetrasaccharide is expressed on the glycans of several human glycoproteins, including the high-molecular weight salivary mucin MG1 (Mucin 5B), the low-molecular weight salivary mucin MG2 (Mucin 7) and the salivary agglutinin. The epitope specific mAb bound salivary proteins found in human saliva. Salivary proteins were separated by electrophoresis and analyzed for binding to mAb. The epitope is found to be expressed on mucins MG1 and MG2 and on salivary agglutinin; the specific pattern and level of expression on these proteins is different for each of the donors.

name:	iedb
homePage:	http://www.iedb.org

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