Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1105 |
| landingPage: |
http://www.iedb.org/assay/15255 |
| type: |
Literature
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| publicationVenue: |
FEBS Lett
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| dates: |
2005
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| study type: | b cell assays |
| subject species: | SARS coronavirus |
| fullName: |
Wei Lu
Xiao-Dong Wu
Mu De Shi
Rui Fu Yang
You Yu He
Chao Bian
Tie Liu Shi
Sheng Yang
Xue-Liang Zhu
Wei-Hong Jiang
Yi Xue Li
Lin-Chen Yan
Yong Yong Ji
Ying Lin
Guo-Mei Lin
Lin Tian
Jin Wang
Hong Xia Wang
You Hua Xie
Gang Pei
Jia Rui Wu
Bing Sun
|
| method: |
western blot
|
| name: |
Synthetic peptides derived from SARS coronavirus S protein with diagnostic and therapeutic potential.
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| description: |
The sera from peptide-immunized rabbits showed specific binding to the S protein and its S1 and S2 fragments. The S protein and its fragments were isolated from E. coli expressed protein. Binding was also observed to the native S protein from the lysates of SARS-CoV infected Vero E6 cells. The peptide was also analyzed for its ability to inhibit syncytia formation as an indicator of its virus neutralizing activity (syncytia formation was used to mimic the SARS-CoV infection procedure). No significant syncytia formation inhibition was observed.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
