Novel human monoclonal antibody combination effectively neutralizing natural rabies virus variants and individual in vitro escape mutants.

Title:

Novel human monoclonal antibody combination effectively neutralizing natural rabies virus variants and individual in vitro escape mutants.

identifier:	15349
description:	epitope description:KLCGVL antigen name:Glycoprotein host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	15994800

study type:	b cell assays
subject species:	Rabies lyssavirus

fullName:	Alexander B H Bakker Wilfred E Marissen R Arjen Kramer Amy B Rice William C Weldon Michael Niezgoda Cathleen A Hanlon Sandra Thijsse Harold H J Backus John de Kruif Bernhard Dietzschold Charles E Rupprecht Jaap Goudsmit

method:	in vivo assay

name:	Novel human monoclonal antibody combination effectively neutralizing natural rabies virus variants and individual in vitro escape mutants.
description:	Adoptive transfer the epitope specific mAb protected Syrian hamster vaccinated with rabies vaccine from infection with the lethal rabies virus (COSRV), and no clear dose-response effect was observed.

name:	iedb
homePage:	http://www.iedb.org

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.