Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/596 |
| landingPage: |
http://www.iedb.org/assay/11883 |
| type: |
Literature
|
| publicationVenue: |
Infect Immun
|
| dates: |
2005
|
| study type: | b cell assays |
| subject species: |
| fullName: |
Ulrike K Buchwald
Andrew Lees
Michael Steinitz
Liise-Anne Pirofski
|
| method: |
ELISA
|
| name: |
A peptide mimotope of type 8 pneumococcal capsular polysaccharide induces a protective immune response in mice.
|
| description: |
Preimmune serum from PUB1 conjugate-immunized mice reacted with type 8 PS at titers of 1:540 for IgM. On day 7, type 8 PS-specific IgM in the PUB1-TT and PUB1-TT/CpG-Al groups increased 5.5- to 6.5-fold compared to preimmune serum values. Type 8 PS-specific IgM peaked on day 14, with titers of 1:7,000 in the PUB1-TT group and 1:8,000 in the PUB1-TT/CpG-Al group and decreased thereafter. A slight boost response was observed on day 49, 14 days after the second boost.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
