Universal influenza B vaccine based on the maturational cleavage site of the hemagglutinin precursor.

Title:

Universal influenza B vaccine based on the maturational cleavage site of the hemagglutinin precursor.

identifier:	15953
description:	epitope description:PAKLLKERGFFGAIAGFLE antigen name:Hemagglutinin host organism:Mus musculus BALB/c
aggregation:	instance of dataset
availability:	available
primaryPublications:	15919893

study type:	b cell assays
subject species:	Influenza B virus

fullName:	Elisabetta Bianchi Xiaoping Liang Paolo Ingallinella Marco Finotto Michael A Chastain Jiang Fan Tong-Ming Fu Hong Chang Song Melanie S Horton Daniel C Freed Walter Manger Emily Wen Li Shi Roxana Ionescu Colleen Price Marc Wenger Emilio A Emini Riccardo Cortese Gennaro Ciliberto John W Shiver Antonello Pessi

method:	in vivo assay

name:	Universal influenza B vaccine based on the maturational cleavage site of the hemagglutinin precursor.
description:	Adoptive transfer of serum from B-HA0 vaccine immunized mice protected recipient mice from infection with Influenza B virus/Ann Arbor/4/55 with 90% survival, compared to 10% in the control group. This protection depended on the FcgammaR effector pathway.

name:	iedb
homePage:	http://www.iedb.org

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