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identifier: 17696
description:
epitope description:beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc
antigen name:alpha-N-acetylneuraminosyl-(2->3)-[beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')--N-acylsphingosine
host organism:Mus musculus BALB/c GalNAc Transferase null
aggregation:
instance of dataset
availability:
available
primaryPublications: 12183547
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/954
landingPage: http://www.iedb.org/assay/17696
type:
Literature
publicationVenue:
Infect Immun
dates:
2002
study type: b cell assays
subject species: Vertebrata
fullName:
Tyrone Bowes
Eric R Wagner
Judith Boffey
Dawn Nicholl
Lynne Cochrane
Mustapha Benboubetra
Joe Conner
Keiko Furukawa
Koichi Furukawa
Hugh J Willison
method:
ELISA
name:
Tolerance to self gangliosides is the major factor restricting the antibody response to lipopolysaccharide core oligosaccharides in Campylobacter jejuni strains associated with Guillain-Barré syndrome.
description:
The epitope is deduced to be the carbohydrate moiety from the lack of cross-reactivity towards other gangliosides.
IgM responses were not significantly cross-reactive between the LPS immunogen and the ganglioside antigen.

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