Identification of protective epitopes on ebola virus glycoprotein at the single amino acid level by using recombinant vesicular stomatitis viruses.

Title:

Identification of protective epitopes on ebola virus glycoprotein at the single amino acid level by using recombinant vesicular stomatitis viruses.

Dataset

identifier:	22539
description:	epitope description:R134, F194, L199 antigen name:Envelope glycoprotein host organism:Mus musculus BALB/c antibody name:226/8.1
aggregation:	instance of dataset
availability:	available
primaryPublications:	12502822

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/272
landingPage:	http://www.iedb.org/assay/22539

Publication

type:	Literature
publicationVenue:	J Virol
dates:	2003

Dimension

study type:	b cell assays
subject species:	Zaire ebolavirus

Person

fullName:	Ayato Takada Heinz Feldmann Ute Stroeher Mike Bray Shinji Watanabe Hiroshi Ito Martha McGregor Yoshihiro Kawaoka

Data Type

method:	biological activity

Study

name:	Identification of protective epitopes on ebola virus glycoprotein at the single amino acid level by using recombinant vesicular stomatitis viruses.
description:	The epitope was deduced. The epitope specific mAb neutralized the infectivity of recombinant vesicular stomatitis virus (VSV) containing GP-encoding gene from species Zaire. The epitope was deduced by loss of reactivity when VSV expressed GP with the epitopic residue mutated, as found in escape mutants.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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