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Title: Identification and characterization of B-cell epitopes of IpaC, an invasion-associated protein of Shigella flexneri.
identifier: 1068494
description:
epitope description:TLTPENTL
antigen name:Invasin IpaC
host organism:Mus musculus BALB/c
antibody name:H8
aggregation:
instance of dataset
availability:
available
primaryPublications: 1373401
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1000890
landingPage: http://www.iedb.org/assay/1068494
type:
Literature
publicationVenue:
Infect Immun
dates:
1992
study type: b cell assays
subject species: Shigella flexneri
fullName:
A Phalipon
J Arondel
F Nato
S Rouyre
J C Mazie
P J Sansonetti
method:
cross blocking
name:
Identification and characterization of B-cell epitopes of IpaC, an invasion-associated protein of Shigella flexneri.
description:
A competition assay was performed between monoclonal antibodies and sera from convalescent humans and monkeys for binding to invasion plasmid antigen C (IpaC). The increasing binding of the monoclonal antibodies in thepresence of decreasing concentrations of sera from convalescent humans and monkeys indicates that competition occurs and that the epitope recognized by the monoclonal antibody is also recognized by sera from convalescent humans and monkeys.

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