A synthetic peptide to the E glycoprotein of Murray Valley encephalitis virus defines multiple virus-reactive T- and B-cell epitopes.

Title:

A synthetic peptide to the E glycoprotein of Murray Valley encephalitis virus defines multiple virus-reactive T- and B-cell epitopes.

identifier:	1066624
description:	epitope description:EILVEFEEPHATKQS antigen name:Genome polyprotein host organism:Mus musculus C57BL/6
aggregation:	instance of dataset
availability:	available
primaryPublications:	1383567

study type:	b cell assays
subject species:	Murray Valley encephalitis virus

fullName:	J H Mathews J T Roehrig J R Brubaker A R Hunt J E Allan

method:	ELISA

name:	A synthetic peptide to the E glycoprotein of Murray Valley encephalitis virus defines multiple virus-reactive T- and B-cell epitopes.
description:	Epitopes were analyzed for putative T-cell epitopes using 2 algorithms: Rothbard's motif in association with alpha helix formation, and AMPHI, a program based on the amphipathic helical characteristics of the peptides. Peptide 6-2 contained the entire AMPHI-predicted sequence. The Swiss Pot sequence is from MVE 1-51, but the strain used in the paper is Ord River. Anti-peptide antisera also reacted with peptide 6 STEWRNREILVEFEEPHATKQS, 6-2 LVEFEEPHATKQS and 6-3 EILVEFEEPHATKQS, but did not react with 6-1 STEWRNREILVE.

name:	iedb
homePage:	http://www.iedb.org

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