A chimeric influenza virus expressing an epitope of outer membrane protein F of Pseudomonas aeruginosa affords protection against challenge with P. aeruginosa in a murine model of chronic pulmonary infection.

Title:

Dataset

identifier:	24116
description:	epitope description:AEGRAINRRVE antigen name:Outer membrane porin F host organism:Mus musculus
aggregation:	instance of dataset
availability:	available
primaryPublications:	9673294

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1466
landingPage:	http://www.iedb.org/assay/24116

Publication

type:	Literature
publicationVenue:	Infect Immun
dates:	1998

Dimension

study type:	b cell assays
subject species:	Pseudomonas aeruginosa

Person

fullName:	J Staczek H E Gilleland Jr L B Gilleland R N Harty A Garcí a-Sastre O G Engelhardt P Palese

Data Type

method:	in vivo assay

Study

name:	A chimeric influenza virus expressing an epitope of outer membrane protein F of Pseudomonas aeruginosa affords protection against challenge with P. aeruginosa in a murine model of chronic pulmonary infection.
description:	The challenge assay was assed by counting the number of lisions in immunized animals vs. control. Responder are animals without or less number of lesions in their lungs compared to control. Protection was less in group of animals immunized with a lesser amount of immunogen.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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