Influence of the amino acid differences between the hemagglutinin HA1 domains of influenza virus H1N1 strains on their reaction with antibody.

Title:

Influence of the amino acid differences between the hemagglutinin HA1 domains of influenza virus H1N1 strains on their reaction with antibody.

identifier:	24204
description:	epitope description:K90, K91 antigen name:Hemagglutinin host organism:Gallus gallus
aggregation:	instance of dataset
availability:	available
primaryPublications:	10089053

study type:	b cell assays
subject species:	Influenza A virus (A/USSR/90/1977(H1N1))

fullName:	J Drescher R Aron

method:	biological activity

name:	Influence of the amino acid differences between the hemagglutinin HA1 domains of influenza virus H1N1 strains on their reaction with antibody.
description:	Antibodies raised against strain A/FM/1/47 of influenza virus, where residue K82 is mutated to a R residue, are shown to have a decrease in the hemagglutination inhibition titers when assayed with strains harboring this residue, but the equilibrium constant (K) of the reaction is higher with the strains harboring this epitope.

name:	iedb
homePage:	http://www.iedb.org

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