Structural assignment of novel and immunodominant antigenic sites in the neutralizing antibody response of CBA/Ca mice to influenza hemagglutinin.

Title:

Structural assignment of novel and immunodominant antigenic sites in the neutralizing antibody response of CBA/Ca mice to influenza hemagglutinin.

Dataset

identifier:	1003480
description:	epitope description:S193 antigen name:Hemagglutinin host organism:Mus musculus CBA/Ca antibody name:29.1, 37.1, 5.1.1, 21.3, 8.1, 4.3, 5.1, 8.2, 2.1
aggregation:	instance of dataset
availability:	available
primaryPublications:	1706753

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1000086
landingPage:	http://www.iedb.org/assay/1003480

Publication

type:	Literature
publicationVenue:	J Exp Med
dates:	1991

Dimension

study type:	b cell assays
subject species:	Influenza A virus (A/X-31(H3N2))

Person

fullName:	C A Smith B C Barnett D B Thomas F

Data Type

method:	biological activity

Study

name:	Structural assignment of novel and immunodominant antigenic sites in the neutralizing antibody response of CBA/Ca mice to influenza hemagglutinin.
description:	Positive responses were found with monoclonal antibodies generated from three mice. Positive responses were generated against two mutants, one with an Isoleucine substitution, and a second with an Arginine substitution.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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