Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1000151 |
| landingPage: |
http://www.iedb.org/assay/1003791 |
| type: |
Literature
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| publicationVenue: |
J Clin Microbiol
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| dates: |
2005
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| study type: | b cell assays |
| subject species: | Influenza B virus (B/Osaka/983/97-V3) |
| fullName: |
Naoko Nakagawa
Ritsuko Kubota
Yoshinobu Okuno
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| method: |
biological activity
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| name: |
Variation of the conserved neutralizing epitope in influenza B virus victoria group isolates in Japan.
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| description: |
Monoclonal antibody 10B8 exhibited hemagglutination-inhibition activity against the B/Osaka/983/1997 strain, but it did not react with five B/Victoria isolates (DDBJ accession no. AB081570, AB081571, AB083182, AB083183, and AB196144). Genetic analysis revealed a single amino acid substitution at position 164 of the epitope in several of these isolates. A second monoclonal antibody, 10D7, generated against one of these new isolates, showed similar reactivity patterns.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
