Mechanism of antigenic variation in an individual epitope on influenza virus N9 neuraminidase. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Mechanism of antigenic variation in an individual epitope on influenza virus N9 neuraminidase.

Dataset

identifier:	1004720
description:	epitope description:S368, S373, N400 antigen name:Neuraminidase host organism:Mus musculus BALB/c antibody name:NC41
aggregation:	instance of dataset
availability:	available
primaryPublications:	1700825

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1000091
landingPage:	http://www.iedb.org/assay/1004720

Publication

type:	Literature
publicationVenue:	J Virol
dates:	1990

Dimension

study type:	b cell assays
subject species:	Influenza A virus (A/tern/Australia/G70C/1975(H11N9))

Person

fullName:	G M Air W G Laver R G Webster

Data Type

method:	biological activity

Study

name:	Mechanism of antigenic variation in an individual epitope on influenza virus N9 neuraminidase.
description:	The assay is the selection of escape variants by a monoclonal antibody (NC41). Sequencing escape variant proteins reveals key amino acid residues that are important in the binding of the monoclonal antibody (NC41) to the original virus (wt).

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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