The structure of an antigenic determinant in a protein. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

The structure of an antigenic determinant in a protein.

Dataset

identifier:	1004256
description:	epitope description:KWDLFVERSK antigen name:Hemagglutinin host organism:Mus musculus 129 GIX+ antibody name:23B05
aggregation:	instance of dataset
availability:	available
primaryPublications:	6204768

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1000217
landingPage:	http://www.iedb.org/assay/1004256

Publication

type:	Literature
publicationVenue:	Cell
dates:	1984

Dimension

study type:	b cell assays
subject species:	Influenza A virus (A/Victoria/3/1975(H3N2))

Person

fullName:	I A Wilson H L Niman R A Houghten A R Cherenson M L Connolly R A Lerner

Data Type

method:	ELISA

Study

name:	The structure of an antigenic determinant in a protein.
description:	This peptide corresponds to the region called Site 3 by the authors. This sequence is essentially buried in the native structure of HA, except for some of the atoms of residues at each end. At the carboxyl-end, R90, S91 and K92 form a sharp protrusion with approximate dimensions 14 x 9 x 8A. Hybridoma supernatants were assayed against overlapping peptides covering the 36 aa-immunizing pepitde. This mAb was maped to this epitope. The immunizing peptide was also recognized in ELISA.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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