Anti-peptide antibodies detect steps in a protein conformational change: low-pH activation of the influenza virus hemagglutinin.

Title:

Anti-peptide antibodies detect steps in a protein conformational change: low-pH activation of the influenza virus hemagglutinin.

identifier:	1008058
description:	epitope description:LCLGHHAVPNGTLVKTITNDQIEVTNATELVQSSSTGKI antigen name:Hemagglutinin host organism:Oryctolagus cuniculus antibody name:3
aggregation:	instance of dataset
availability:	available
primaryPublications:	2447101

study type:	b cell assays
subject species:	Influenza A virus (A/Victoria/3/1975(H3N2))

fullName:	J M White I A Wilson

method:	immunoprecipitation

name:	Anti-peptide antibodies detect steps in a protein conformational change: low-pH activation of the influenza virus hemagglutinin.
description:	Since the amino acid sequences were not available in the curated manuscript, the sequence presented in this record was obtained in a paper by Green et al, 1982. We have used the amino acid positions presented by authors to determine the putative amino acid sequence. Since the X-47 reassortant used in this study is not listed on NCBI taxonomy, the source provided is for the parental strain VIctoria/3/75. Treatment of HA protein at low pH significantly increased reactivity of anti-peptide binding

name:	iedb
homePage:	http://www.iedb.org

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