Three-dimensional structure of an antigenic mutant of the influenza virus haemagglutinin. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Three-dimensional structure of an antigenic mutant of the influenza virus haemagglutinin.

Dataset

identifier:	1005200
description:	epitope description:G146 antigen name:Hemagglutinin host organism:Mus musculus antibody name:HC3a
aggregation:	instance of dataset
availability:	available
primaryPublications:	6207440

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1000303
landingPage:	http://www.iedb.org/assay/1005200

Publication

type:	Literature
publicationVenue:	Nature
dates:	1984

Dimension

study type:	b cell assays
subject species:	Influenza A virus (A/X-31(H3N2))

Person

fullName:	M Knossow R S Daniels A R Douglas J J Skehel D C Wiley

Data Type

method:	biological activity

Study

name:	Three-dimensional structure of an antigenic mutant of the influenza virus haemagglutinin.
description:	A monoclonal antibody was used to select a viral escape variant. Sequence analysis of the variant revealed an amino acid substitution at position 146. A similar result was reportedly obtained in ELISA antibody assays.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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