Immunogenic structure of the influenza virus hemagglutinin. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Immunogenic structure of the influenza virus hemagglutinin.

Dataset

identifier:	1008603
description:	epitope description:CLGHHAVPNGTLVKTITNDQIEVTNATELVQSSSTGKIC antigen name:Hemagglutinin host organism:Oryctolagus cuniculus
aggregation:	instance of dataset
availability:	available
primaryPublications:	6176330

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1000193
landingPage:	http://www.iedb.org/assay/1008603

Publication

type:	Literature
publicationVenue:	Cell
dates:	1982

Dimension

study type:	b cell assays
subject species:	Influenza A virus (A/Victoria/3/1975(H3N2))

Person

fullName:	N Green H Alexander A Olson S Alexander T M Shinnick J G Sutcliffe R A Lerner

Data Type

method:	ELISA

Study

name:	Immunogenic structure of the influenza virus hemagglutinin.
description:	The peptide synthesized included a N-terminal tyrosine not present in the primary HA sequence. The actual sequence used is YCLGHHAVPNGTLVKTITNDQIEVTNATELVQSSSTGKIC. The source reported by the authors is X47 reassortant, where the HA molecule is derived from the parent strain Victoria/3/75. The actual virus strain used in the assay is the X-47 reassortant. Negative responses were obtained with sera from animals immunized with 1 mg uncoupled (without KLH conjugation) peptide per dose.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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