An antigenic map of the haemagglutinin of the influenza Hong Kong subtype (H3N2), constructed using mouse monoclonal antibodies.

Title:

An antigenic map of the haemagglutinin of the influenza Hong Kong subtype (H3N2), constructed using mouse monoclonal antibodies.

identifier:	1008735
description:	epitope description:Y172, S174 antigen name:Hemagglutinin host organism:Mus musculus BALB/c
aggregation:	instance of dataset
availability:	available
primaryPublications:	6205255

study type:	b cell assays
subject species:	Influenza A virus (A/Victoria/3/1975(H3N2))

fullName:	P A Underwood

method:	biological activity

name:	An antigenic map of the haemagglutinin of the influenza Hong Kong subtype (H3N2), constructed using mouse monoclonal antibodies.
description:	These residues are part of the target area B, which is composed in this strain by residues G129, Y155, S157, G158, S159, N193, located at the top of the HA1 molecule."""" Swiss-prot entry includes a 16-aa signal peptide. The possible binding sites (target areas) of a panel of 25 anti-VIC75 mAbs was determined by correlation of cross-reactivity of mAbs with sequence differences in variants of the hemagglutinin in heterologous strains of the influenza subtype H3N2. One of these antibodies, named group 8, is affected by mutations at the epitopic residues.

name:	iedb
homePage:	http://www.iedb.org

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