Use of bacterial expression cloning to define the amino acid sequences of antigenic determinants on the G2 glycoprotein of Rift Valley fever virus.

Title:

Use of bacterial expression cloning to define the amino acid sequences of antigenic determinants on the G2 glycoprotein of Rift Valley fever virus.

Dataset

identifier:	1032515
description:	epitope description:DCNFCRQMTGASLKKGSYPL antigen name:Rift Valley fever phlebovirus protein host organism:Mus musculus antibody name:I
aggregation:	instance of dataset
availability:	available
primaryPublications:	2422392

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1000510
landingPage:	http://www.iedb.org/assay/1032515

Publication

type:	Literature
publicationVenue:	J Virol
dates:	1986

Dimension

study type:	b cell assays
subject species:	Rift Valley fever virus

Person

fullName:	K Keegan M S Collett

Data Type

method:	immunoprecipitation

Study

name:	Use of bacterial expression cloning to define the amino acid sequences of antigenic determinants on the G2 glycoprotein of Rift Valley fever virus.
description:	Epitope mapping was performed with molecular cloning of truncated glycoprotein-coding sequences in a bacterial expression plasmid. The monoclonal antibody was reportedly able to neutralize virus infectivity and to confer passive protection to mice challenged with lethal viral doses.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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