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Title: Use of bacterial expression cloning to define the amino acid sequences of antigenic determinants on the G2 glycoprotein of Rift Valley fever virus.
identifier: 1032516
description:
epitope description:DCNFCRQMTGASLKKGSYPL
antigen name:Rift Valley fever phlebovirus protein
host organism:Mus musculus
antibody name:I
aggregation:
instance of dataset
availability:
available
primaryPublications: 2422392
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1000510
landingPage: http://www.iedb.org/assay/1032516
type:
Literature
publicationVenue:
J Virol
dates:
1986
study type: b cell assays
subject species: Rift Valley fever virus
fullName:
K Keegan
M S Collett
method:
immunoprecipitation
name:
Use of bacterial expression cloning to define the amino acid sequences of antigenic determinants on the G2 glycoprotein of Rift Valley fever virus.
description:
The monoclonal antibody reacted with a standard detergent cell lysate, but not with a SDS-denatured cell lysate. The monoclonal antibody was further shown to have a similar reactivity pattern with bacterial-expressed protein, which was subsequently employed for epitope mapping. The monoclonal antibody was reportedly able to neutralize virus infectivity and to confer passive protection to mice challenged with lethal viral doses.

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