Vinculin proteolysis unmasks an ActA homolog for actin-based Shigella motility. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Vinculin proteolysis unmasks an ActA homolog for actin-based Shigella motility.

Dataset

identifier:	1036159
description:	epitope description:FEFPPPPTDE antigen name:Actin assembly-inducing protein host organism:Oryctolagus cuniculus antibody name:FS-1
aggregation:	instance of dataset
availability:	available
primaryPublications:	9298981

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1000474
landingPage:	http://www.iedb.org/assay/1036159

Publication

type:	Literature
publicationVenue:	J Cell Biol
dates:	1997

Dimension

study type:	b cell assays
subject species:	Listeria monocytogenes

Person

fullName:	R O Laine W Zeile F Kang D L Purich F S Southwick

Data Type

method:	western blot

Study

name:	Vinculin proteolysis unmasks an ActA homolog for actin-based Shigella motility.
description:	The authors indicated that the cross-reactivity of the monoclonal antiboty FS-1 with the 90-kD vinculin protein was probably due to the presence of a peptide (Vinc-1: PDFPPPPPDL) in the vinculin protein which shows a strong homology to the oligoproline sequences of listeria ActA.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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