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identifier: 1069436
description:
epitope description:HKYSWK
antigen name:Genome polyprotein
host organism:Mus musculus
antibody name:15F3-1
aggregation:
instance of dataset
availability:
available
primaryPublications: 7537702
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1000831
landingPage: http://www.iedb.org/assay/1069436
type:
Literature
publicationVenue:
FEMS Microbiol Lett
dates:
1995
study type: b cell assays
subject species: Dengue virus 1
fullName:
Z J Yao
M C Kao
K C Loh
M C Chung
method:
antigen inhibition
name:
A serotype-specific epitope of dengue virus 1 identified by phage displayed random peptide library.
description:
A competitive binding inhibition assay was used to determine if the peptide and dengue 1 antigen competed for the same antibody binding site. The antibody was preincubated with the dengue virus. The peptide was synthesized in an eight-chain branched form (8 x HKYSWK) and used to coat the plate. Dengue 1 exhibited significant inhibition, while lysates from dengue viruses 2, 3, and 4 showed no inhibition.

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