T-helper cell epitopes on the E-glycoprotein of dengue 2 Jamaica virus. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

T-helper cell epitopes on the E-glycoprotein of dengue 2 Jamaica virus.

Dataset

identifier:	1212485
description:	epitope description:MRCIGISNRDFVEGVSGGSWVDIVLEHGSC antigen name:Genome polyprotein host organism:Mus musculus NHI Swiss
aggregation:	instance of dataset
availability:	available
primaryPublications:	7505071

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1000575
landingPage:	http://www.iedb.org/assay/1212485

Publication

type:	Literature
publicationVenue:	Virology
dates:	1994

Dimension

study type:	b cell assays
subject species:	Dengue virus 2

Person

fullName:	J T Roehrig P A Risi J R Brubaker A R Hunt B J Beaty D W Trent J H Mathews

Data Type

method:	ELISA

Study

name:	T-helper cell epitopes on the E-glycoprotein of dengue 2 Jamaica virus.
description:	In order to determine which peptides could prime T helper cells for an enhanced antiviral antibody response, NIH-Swiss (outbred) mice were immunized with peptide and then challenges with a sub-optimal dose of DEN 2 virus (determined in Figures 4 and 5). Mice immunized with peptide 1-2 showed poor responsiveness following challenge. Little change in titer was observed between days 5 and 14 post-challenge.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.