Selection of a macaque Fab with framework regions like those in humans, high affinity, and ability to neutralize the protective antigen (PA) of Bacillus anthracis by binding to the segment of PA between residues 686 and 694.

Title:

Dataset

identifier:	1243411
description:	epitope description:PLYISNPNY antigen name:Protective antigen host organism:Macaca fascicularis antibody name:35PA₈₃
aggregation:	instance of dataset
availability:	available
primaryPublications:	16048955

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1001143
landingPage:	http://www.iedb.org/assay/1243411

Publication

type:	Literature
publicationVenue:	Antimicrob Agents Chemother
dates:	2005

Dimension

study type:	b cell assays
subject species:	Bacillus anthracis

Person

fullName:	Emmanuelle Laffly Ludivine Danjou Florence Condemine Dominique Vidal Emmanuel Drouet Marie-Paule Lefranc Chantal Bottex Philippe Thullier

Data Type

method:	surface plasmon resonance (SPR)

Study

name:	Selection of a macaque Fab with framework regions like those in humans, high affinity, and ability to neutralize the protective antigen (PA) of Bacillus anthracis by binding to the segment of PA between residues 686 and 694.
description:	The affinity of the 35PA83 was measured by surface plasmon resonance using Biacore.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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