Identification of immunodominant epitopes on the membrane protein of the severe acute respiratory syndrome-associated coronavirus.

Title:

Identification of immunodominant epitopes on the membrane protein of the severe acute respiratory syndrome-associated coronavirus.

identifier:	1243896
description:	epitope description:YYKLGASQRVGTDSGFAA antigen name:Membrane protein host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	16081901

study type:	b cell assays
subject species:	SARS coronavirus

fullName:	Yuxian He Yusen Zhou Pamela Siddiqui Jinkui Niu Shibo Jiang

method:	ELISA

name:	Identification of immunodominant epitopes on the membrane protein of the severe acute respiratory syndrome-associated coronavirus.
description:	E1 glycoprotein is also referred to as matrix glycoprotein or membrane glycoprotein. The sequence of the epitope was derived from the genomic sequence of the M protein of SARS described in Marra M. et al. Science 2003. Peptides that were less than 10% (4 responders out of 40 subjects) were considered negative.In another, experiment, a mixture of proteins purified from viral lysates of SARS coronavirus were used as coating antigen in ELISA. A total of forty serum samples were obtained from SARS patients and were tested positive by ELISA. All samples tested positive.

name:	iedb
homePage:	http://www.iedb.org

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