The 2beta2-2beta3 loop of anthrax protective antigen contains a dominant neutralizing epitope. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

The 2beta2-2beta3 loop of anthrax protective antigen contains a dominant neutralizing epitope.

Dataset

identifier:	1244205
description:	epitope description:SFFD antigen name:Protective antigen host organism:Mus musculus BALB/c antibody name:5E1, 2A8
aggregation:	instance of dataset
availability:	available
primaryPublications:	16460675

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1001087
landingPage:	http://www.iedb.org/assay/1244205

Publication

type:	Literature
publicationVenue:	Biochem Biophys Res Commun
dates:	2006

Dimension

study type:	b cell assays
subject species:	Bacillus anthracis

Person

fullName:	Jun Zhang Junjie Xu Guanlin Li Dayong Dong Xiaohong Song Qiang Guo Jian Zhao Ling Fu Wei Chen

Data Type

method:	biological activity

Study

name:	The 2beta2-2beta3 loop of anthrax protective antigen contains a dominant neutralizing epitope.
description:	This peptide represents the consensus sequence of selected phage clones. Both monoclonal antibodies exhibited strong anthrax toxin-neutralizing activities. Monoclonal antibody 2A8 belongs to the IgG2b subclass, while 5E1 belongs to the IgG1 subclass.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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