Identification and antigenic epitope mapping of immunodominant region amino residues 510 to 672 on the spike protein of the severe acute respiratory syndrome coronavirus.

Title:

Identification and antigenic epitope mapping of immunodominant region amino residues 510 to 672 on the spike protein of the severe acute respiratory syndrome coronavirus.

Dataset

identifier:	1244207
description:	epitope description:FQQFGRDVSDFTDSVRDPKT antigen name:Spike glycoprotein host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	16101348

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1001139
landingPage:	http://www.iedb.org/assay/1244207

Publication

type:	Literature
publicationVenue:	DNA Cell Biol
dates:	2005

Dimension

study type:	b cell assays
subject species:	SARS coronavirus

Person

fullName:	Rong-Hong Hua Yun-Feng Wang Zhi-Gao Bu Yan-Jun Zhou Jin-Ying Ge Xi-Jun Wang Guang-Zhi Tong

Data Type

method:	ELISA

Study

name:	Identification and antigenic epitope mapping of immunodominant region amino residues 510 to 672 on the spike protein of the severe acute respiratory syndrome coronavirus.
description:	Convalescent sera was used to test for reactivity to this peptide. Subsequently, the test to see if the reactivity could be competed with the adjacent peptide S1C3(539-559) showed negative results, suggesting this epitope is a single antigenic region.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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