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Title: Inducing systemic and mucosal immune responses to B-T construct of F1 antigen of Yersinia pestis in microsphere delivery.
identifier: 1244233
description:
epitope description:ITIMDNGNIDTELLVGTLTLGGY
antigen name:F1 capsule antigen
host organism:Mus musculus Outbred
aggregation:
instance of dataset
availability:
available
primaryPublications: 16476510
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1001080
landingPage: http://www.iedb.org/assay/1244233
type:
Literature
publicationVenue:
Vaccine
dates:
2006
study type: b cell assays
subject species: Yersinia pestis 195/P
fullName:
Vinita Tripathi
K T Chitralekha
Anand R Bakshi
Deepak Tomar
R A Deshmukh
M A Baig
D N Rao
method:
ELISA
name:
Inducing systemic and mucosal immune responses to B-T construct of F1 antigen of Yersinia pestis in microsphere delivery.
description:
Low IgA responses were seen against a construct (B5T1) including this B cell epitope linked to by two G residues to a T helper epitope from the same protein F1, in sera from outbred mice immunized with that construct entrapped in a poly-DL-lactide-co-glycolide (PLG) microparticle, by intramuscular immunization. Similar responses were obtained by the use of 2 different Thelper epitopes as part of the construct (T1: VNGENLVGDDVVLAT or T2: TGSQDFFVRSIG).

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