Fine mapping of a peptide sequence containing an antigenic site conserved among arenaviruses. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Fine mapping of a peptide sequence containing an antigenic site conserved among arenaviruses.

Dataset

identifier:	1244419
description:	epitope description:CNYSKFWYLEHAK antigen name:Pre-glycoprotein polyprotein GP complex host organism:Mus musculus antibody name:33.6, 83.6
aggregation:	instance of dataset
availability:	available
primaryPublications:	2452517

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1000852
landingPage:	http://www.iedb.org/assay/1244419

Publication

type:	Literature
publicationVenue:	Virology
dates:	1988

Dimension

study type:	b cell assays
subject species:	Lymphocytic choriomeningitis mammarenavirus

Person

fullName:	E L Weber M J Buchmeier

Data Type

method:	immuno staining

Study

name:	Fine mapping of a peptide sequence containing an antigenic site conserved among arenaviruses.
description:	This peptide is found in different species of arenavirus family. Phenylalanine at position 375 seems to be Lassa virus-specific for the binding of monoclonal antibody 9-7.9. Lassa-specific F to Y change at position 375 resulted in almost total loss of binding by MAb 9-7.9 without loss of 33.6 binding.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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