Mapping of B epitopes in GRA4, a dense granule antigen of Toxoplasma gondii and protection studies using recombinant proteins administered by the oral route.

Title:

Mapping of B epitopes in GRA4, a dense granule antigen of Toxoplasma gondii and protection studies using recombinant proteins administered by the oral route.

Dataset

identifier:	1244675
description:	epitope description:KGFGGTRTSTAPAEAGKTELDDGYRPPPFNPRPSPYAELLKDLERMRKE antigen name:Other Toxoplasma gondii protein host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	9618729

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1001017
landingPage:	http://www.iedb.org/assay/1244675

Publication

type:	Literature
publicationVenue:	Parasite Immunol
dates:	1998

Dimension

study type:	b cell assays
subject species:	Toxoplasma gondii

Person

fullName:	M N Mé vé lec O Mercereau-Puijalon D Buzoni-Gatel I Bourguin T Chardè s J F Dubremetz D Bout

Data Type

method:	ELISA

Study

name:	Mapping of B epitopes in GRA4, a dense granule antigen of Toxoplasma gondii and protection studies using recombinant proteins administered by the oral route.
description:	The authors indicate that the epitope sequence they provided are amino acids 296-345 of GRA4. But in fact, this sequence matches with amino acids 297-345 in the existent SwissProt record of GRA4 (the source protein). Sera from Toxoplasma gondii-infected humans reacted positively with the epitope (peptide) by ELISA. Truncation analysisdemonstrated recognition of an epitope within residues 334-345.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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