Development of a plant-derived subunit vaccine candidate against hepatitis C virus. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Development of a plant-derived subunit vaccine candidate against hepatitis C virus.

Dataset

identifier:	1245900
description:	epitope description:QTTVVGGSQSHTVRGLTSLFSPGASQN host organism:Mus musculus C57BL/6
aggregation:	instance of dataset
availability:	available
primaryPublications:	11205105

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1001178
landingPage:	http://www.iedb.org/assay/1245900

Publication

type:	Literature
publicationVenue:	Arch Virol
dates:	2000

Dimension

study type:	b cell assays
subject species:

Person

fullName:	L G Nemchinov T J Liang M M Rifaat H M Mazyad A Hadidi J M Keith

Data Type

method:	ELISA

Study

name:	Development of a plant-derived subunit vaccine candidate against hepatitis C virus.
description:	The HCV HRV1 peptide is a cross-reactive mimotope of the Hepatitis C virus envelope protein which antigenically mimics a large number of natural HCV HVR1 variants. Mice were immunized with TMV/CTB-HRV1-infected plant extract in order to estimate the immunogenic potential of the plant-produced recombinant proteins. Immunized mice developed a specific HRV1 response with an average titer of 1:800 (Day 28 and 74).

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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