Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1246116 |
| description: |
epitope description:4,6-dideoxy-4-(3-deoxy-L-glycero-tetronamido)-alpha-D-Manp2Me-(1->2)-4,6-dideoxy-4-(3-deoxy-L-glycero-tetronamido)-alpha-D-Manp-(1->2)-4,6-dideoxy-4-(3-deoxy-L-glycero-tetronamido)-alpha-D-Manp
antigen name:lipopolysaccharide
host organism:Mus musculus BALB/c
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
16098493 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1001140 |
| landingPage: |
http://www.iedb.org/assay/1246116 |
| type: |
Literature
|
| publicationVenue: |
Carbohydr Res
|
| dates: |
2005
|
| study type: | b cell assays |
| subject species: | Vibrio cholerae O1 serotype Ogawa |
| fullName: |
Rina Saksena
Xingquan Ma
Terri K Wade
Pavol Ková
c
William F Wade
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| method: |
ELISA
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| name: |
Effect of saccharide length on the immunogenicity of neoglycoconjugates from synthetic fragments of the O-SP of Vibrio cholerae O1, serotype Ogawa.
|
| description: |
This trisaccharide is representative of the structure of the non-reducing end of the O-PS from V. cholerae O1 Ogawa LPS.
Epitope-specific antisera IgM was tested for cross-reactivity with Inaba LPS, that is similar to the Ogawa type but differs by the absence of the 2-O-methyl group at the terminal sugar. The specificity of the response varies among groups injected with different BSA/CHO ratios, but no direct correlation can be made. The existence of cross-reactivity suggests that B cell epitopes in the Ogawa glycoconjugates were not formed solely by the terminal sugar O-methyl group.
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| name: |
iedb
|
| homePage: |
http://www.iedb.org |
