Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1005373 |
| landingPage: |
http://www.iedb.org/assay/1467259 |
| type: |
Literature
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| publicationVenue: |
J Allergy Clin Immunol
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| dates: |
2005
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| study type: | b cell assays |
| subject species: | Betula pendula |
| fullName: |
Karin Hufnagl
Birgit Winkler
Margit Focke
Rudolf Valenta
Otto Scheiner
Harald Renz
Ursula Wiedermann
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| method: |
in vivo assay
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| name: |
Intranasal tolerance induction with polypeptides derived from 3 noncross-reactive major aeroallergens prevents allergic polysensitization in mice.
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| description: |
Mice sensitized to Bet v 1 and then treated with the epitope in a mixture with 2 other peptides had a diminished response in an IgE-dependent allergen-specific basophil degranulation assay, as well as IL-4 production. IL-10 production was lower but adoptive transfer experiments showed that tolerance was not transferable by spleen cells.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
