Immunological Data Discovery Index
Advanced Search
  1. << Go Back
Title: Naturally occurring human parainfluenza type 3 viruses exhibit divergence in amino acid sequence of their fusion protein neutralization epitopes and cleavage sites.
identifier: 1468269
description:
epitope description:E101, G398, V509
antigen name:fusion glycoprotein F0
host organism:Mus musculus BALB/c
antibody name:mAb c214
aggregation:
instance of dataset
availability:
available
primaryPublications: 1689394
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1006812
landingPage: http://www.iedb.org/assay/1468269
type:
Literature
publicationVenue:
J Virol
dates:
1990
study type: b cell assays
subject species: Human parainfluenza 3 virus (strain NIH 47885)
fullName:
K V Coelingh
C C Winter
method:
biological activity
name:
Naturally occurring human parainfluenza type 3 viruses exhibit divergence in amino acid sequence of their fusion protein neutralization epitopes and cleavage sites.
description:
Monoclonal antibody c214 was capable of neutralizing the 47885 strain of PIV3. Clinical isolates that escaped neutralization by this antibody had single amino acid changes in one of three separate positions, Glu 101to Asp, Gly 398 to Asp, or Val 509 to Ile, indicating that these positions affect recognition by this antibody.

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.

ImmuneData is supported by the NIAID, Grant HHSN272201700019C. Privacy

ImmuneData is developed by TechWave International, Inc. and UT Health Science Center at Houston