Characterization of a Lactococcus lactis strain that secretes a major epitope of bovine beta-lactoglobulin and evaluation of its immunogenicity in mice.

Title:

Characterization of a Lactococcus lactis strain that secretes a major epitope of bovine beta-lactoglobulin and evaluation of its immunogenicity in mice.

Dataset

identifier:	1469932
description:	epitope description:VYVEELKPTPEGDLEILLQK antigen name:Bos d 5 host organism:Mus musculus BALB/c
aggregation:	instance of dataset
availability:	available
primaryPublications:	14602621

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1005414
landingPage:	http://www.iedb.org/assay/1469932

Publication

type:	Literature
publicationVenue:	Appl Environ Microbiol
dates:	2003

Dimension

study type:	b cell assays
subject species:	Bos taurus

Person

fullName:	Jean-Marc Chatel Sebastien Nouaille Karine Adel-Patient Yves Le Loir Herman Boe Alexandra Gruss Jean-Michel Wal Philippe Langella

Data Type

method:	ELISA

Study

name:	Characterization of a Lactococcus lactis strain that secretes a major epitope of bovine beta-lactoglobulin and evaluation of its immunogenicity in mice.
description:	The epitope is found in Selo et al 1999 Clin Exp Allergy 29:1055 [PMID 10457108] Antigen-specific IgA but not IgG was detected in fecal pellets 3 weeks after inoculation and was not detected further on days 28 and 35. No specific antibodies were detected in sera of immunized mice suggesting that the immune response is restricted to mucosa.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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