Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1007205 |
| landingPage: |
http://www.iedb.org/assay/1470467 |
| type: |
Literature
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| publicationVenue: |
Vaccine
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| dates: |
1999
|
| study type: | b cell assays |
| subject species: | Schistosoma mansoni Puerto Rico |
| fullName: |
L Argiro
S Henri
H Dessein
A J Dessein
A Bourgois
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| method: |
in vivo assay
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| name: |
Induction of a protective immunity against Schistosoma mansoni with ovalbumin-coupled Sm37-5 coadsorbed with granulocyte-macrophage colony stimulating factor (GM-CSF) or IL-12 on alum.
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| description: |
Upon challenge, the level of protection was significant whether GM-CSF (yielded a 32.5-37.9% reduction in the number of worms) or IL-12 (yielded a 27.3% reduction in worm number) was used as adjuvant. In a separate experiment, mice immunized with co-absorption of GM-CSF also had a significant reduction (60.5%) in the number of parasite eggs in the liver after challenge.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
