Antibodies and T cells against synthetic peptides of the C-terminal domain (Hc) of botulinum neurotoxin type A and their cross-reaction with Hc.

Title:

Antibodies and T cells against synthetic peptides of the C-terminal domain (Hc) of botulinum neurotoxin type A and their cross-reaction with Hc.

identifier:	1267625
description:	epitope description:NDRVYINVVVKNKEYRLAT antigen name:Botulinum neurotoxin type A (UniProt:A5HZZ9) host organism:Mus musculus BALB/c
aggregation:	instance of dataset
availability:	available
primaryPublications:	9541456

study type:	b cell assays
subject species:	Clostridium botulinum

fullName:	M Oshima J L Middlebrook M Z Atassi

method:	radio immuno assay (RIA)

name:	Antibodies and T cells against synthetic peptides of the C-terminal domain (Hc) of botulinum neurotoxin type A and their cross-reaction with Hc.
description:	Peptide previously identified as harboring antibody epitope/s recognized in the response against the H_c subunit of BoNT/A in SJL and BALB/c mice. BALB/c mice immunized with this peptide generated Abs to the peptide. Also responses to this peptide are seen in mice immunized with an equimolar mixture of 10 peptides, including this one, that are said to contain T and/or B cell epitopes for mice immunized with Hc subunit of BoNT/A.

name:	iedb
homePage:	http://www.iedb.org

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