Antibodies and T cells against synthetic peptides of the C-terminal domain (Hc) of botulinum neurotoxin type A and their cross-reaction with Hc.

Title:

Antibodies and T cells against synthetic peptides of the C-terminal domain (Hc) of botulinum neurotoxin type A and their cross-reaction with Hc.

identifier:	1267568
description:	epitope description:FNSISLNNEYTIINCMENN antigen name:Botulinum neurotoxin type A (UniProt:A5HZZ9) host organism:Mus musculus SJL
aggregation:	instance of dataset
availability:	available
primaryPublications:	9541456

study type:	b cell assays
subject species:	Clostridium botulinum

fullName:	M Oshima J L Middlebrook M Z Atassi

method:	radio immuno assay (RIA)

name:	Antibodies and T cells against synthetic peptides of the C-terminal domain (Hc) of botulinum neurotoxin type A and their cross-reaction with Hc.
description:	Peptide previously identified as harboring T cell epitope/s recognized in the response against the H_c subunit of BoNT/A in SJL mice. Significant reactivity towards this peptide is seen in SJL mice immunized with this peptide alone or with an equimolar mixture of peptides, including this one, that are said to contain T and/or B cell epitopes for mice immunized with H_c subunit of BoNT/A.

name:	iedb
homePage:	http://www.iedb.org

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