Antibodies and T cells against synthetic peptides of the C-terminal domain (Hc) of botulinum neurotoxin type A and their cross-reaction with Hc.

Title:

Antibodies and T cells against synthetic peptides of the C-terminal domain (Hc) of botulinum neurotoxin type A and their cross-reaction with Hc.

identifier:	1267595
description:	epitope description:DYINRWIFVTITNNRLNNS antigen name:Botulinum neurotoxin type A (UniProt:A5HZZ9) host organism:Mus musculus BALB/c
aggregation:	instance of dataset
availability:	available
primaryPublications:	9541456

study type:	b cell assays
subject species:	Clostridium botulinum

fullName:	M Oshima J L Middlebrook M Z Atassi

method:	radio immuno assay (RIA)

name:	Antibodies and T cells against synthetic peptides of the C-terminal domain (Hc) of botulinum neurotoxin type A and their cross-reaction with Hc.
description:	Peptide previously identified as harboring T cell epitope/s recognized in the response against the H_c subunit of BoNT/A in BALB/c mice. Significant reactivity towards this peptide is seen in BALB/c mice immunized with this peptide alone. Nevertheless, negative results were obtained when mice were immunized with a peptide mixture including this one, that are said to contain T and/or B cell epitopes for mice immunized with Hc subunit of BoNT/A.

name:	iedb
homePage:	http://www.iedb.org

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.