Epitope maps of the Escherichia coli heat-labile toxin B subunit for development of a synthetic oral vaccine.

Title:

Epitope maps of the Escherichia coli heat-labile toxin B subunit for development of a synthetic oral vaccine.

identifier:	1271064
description:	epitope description:EMVIITFKSG antigen name:Heat-labile enterotoxin B chain host organism:Mus musculus C57BL/10
aggregation:	instance of dataset
availability:	available
primaryPublications:	8606092

study type:	b cell assays
subject species:	Escherichia coli ETEC H10407

fullName:	I Takahashi H Kiyono R J Jackson K Fujihashi H F Staats S Hamada J D Clements K L Bost J R McGhee

method:	ELISA

name:	Epitope maps of the Escherichia coli heat-labile toxin B subunit for development of a synthetic oral vaccine.
description:	In order to determine whether the p26-45 20mer contained the original B cell epitope spanning p34-43, p35-44 and p36-45, these peptides were tested against sera from B10 mice immunized with the peptide 26-45. Reactivity was strongest against p36-45 for IgG, IgG1 and IgA, suggesting that the major B cell epitope spans p36-45.

name:	iedb
homePage:	http://www.iedb.org

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