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identifier: 1271071
description:
epitope description:N1155, A1156, S1157, V1159, N1160, Q1162, K1163, E1164, D1166, R1167, N1169, E1170, V1171, K1173, N1174, N1176, E1177, S1178
antigen name:Spike glycoprotein
host organism:Oryctolagus cuniculus New Zealand White
antibody name:HRC1
aggregation:
instance of dataset
availability:
available
primaryPublications: 16697221
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1001321
landingPage: http://www.iedb.org/assay/1271071
type:
Literature
publicationVenue:
J Struct Biol
dates:
2006
study type: b cell assays
subject species: SARS coronavirus
fullName:
Brian Tripet
Daniel J Kao
Scott A Jeffers
Kathryn V Holmes
Robert S Hodges
method:
flow cytometry
name:
Template-based coiled-coil antigens elicit neutralizing antibodies to the SARS-coronavirus.
description:
Anti-HRC1 sera bind to the S protein expressed on the cell surface of CHO cells. This indicates that the native S protein conformation is accessible to the antibody. HRC1 anti-sera was 1.5-fold more effective at binding than HRC2.

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