Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1271723 |
| description: |
epitope description:L-glycero-alpha-D-manno-heptosyl-(1->7)-L-glycero-alpha-D-manno-heptosyl group
antigen name:lipopolysaccharide
host organism:Mus musculus BALB/c
antibody name:MM3
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
1383323 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1000603 |
| landingPage: |
http://www.iedb.org/assay/1271723 |
| type: |
Literature
|
| publicationVenue: |
J Immunol
|
| dates: |
1992
|
| study type: | b cell assays |
| subject species: | Salmonella |
| fullName: |
N A Nnalue
S M Lind
A A Lindberg
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| method: |
antigen inhibition
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| name: |
The disaccharide L-alpha-D-heptose1-->7-L-alpha-D-heptose1-->of the inner core domain of Salmonella lipopolysaccharide is accessible to antibody and is the epitope of a broadly reactive monoclonal antibody.
|
7-L-alpha-D-heptose1-->of the inner core domain of Salmonella lipopolysaccharide is accessible to antibody and is the epitope of a broadly reactive monoclonal antibody.-->
| description: |
Thisdisaccharide is part of the core domain of Salmonella LPS.
The synthetic disaccharide is as effective as the complete core region in inhibiting binding of mAb MM3 to Salmonella typhimurium LPS. It is the most efficient inhibitor tested on a molar basis and is present in all the chemotypes of Salmonella LPS reactive with MM3 and absent from those that did not react. Other experiments support the notion that this epitope is accessible to the antibody in long-chained LPS and in intact bacteria with complete LPS.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
