Identification of two immunogenic domains of the prion protein--PrP--which activate class II-restricted T cells and elicit antibody responses against the native molecule.

Title:

Identification of two immunogenic domains of the prion protein--PrP--which activate class II-restricted T cells and elicit antibody responses against the native molecule.

Dataset

identifier:	1274610
description:	epitope description:NQVYYRPVDQYSNQNNFVHDCVNITIKQHT antigen name:Major prion protein host organism:Mus musculus PrP null
aggregation:	instance of dataset
availability:	available
primaryPublications:	15075357

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1001451
landingPage:	http://www.iedb.org/assay/1274610

Publication

type:	Literature
publicationVenue:	J Leukoc Biol
dates:	2004

Dimension

study type:	b cell assays
subject species:	Mus musculus

Person

fullName:	Sylvie Gregoire Caroline Logre Pat Metharom Estelle Loing Jacques Chomilier Martine Bruley Rosset Pierre Aucouturier Claude Carnaud

Data Type

method:	immuno staining

Study

name:	Identification of two immunogenic domains of the prion protein--PrP--which activate class II-restricted T cells and elicit antibody responses against the native molecule.
description:	Antisera raised against p158-187 surprisingly, did not elicit a good antibody response to membrane PrPC on transfected and activated EL4 cells by indirect immunofluorescence.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.

Related Publications

Feedback?