Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1274558 |
| description: |
epitope description:R297, H298, W299, T300, T301, Q302, G303, C304, N305, C306, P480, D481, Q482, R483, P484, Y485, C486, W487, H488, Y489, P490, P491, K492, P493, C494, Y613, R614, L615, W616, H617, Y618, P619, C620, T621
antigen name:Genome polyprotein
host organism:Homo sapiens
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| aggregation: |
instance of dataset
|
| availability: |
available
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| primaryPublications: |
12882983 |
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1001156 |
| landingPage: |
http://www.iedb.org/assay/1274558 |
| type: |
Literature
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| publicationVenue: |
J Biol Chem
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| dates: |
2003
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| study type: | b cell assays |
| subject species: | Hepatitis C virus genotype 1 |
| fullName: |
Marie-Anne Petit
Colette Jolivet-Reynaud
Estelle Peronnet
Yvonne Michal
Christian Tré
po
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| method: |
ELISA
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| name: |
Mapping of a conformational epitope shared between E1 and E2 on the serum-derived human hepatitis C virus envelope.
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| description: |
C306, C494 and C620 were identified as critical residues. WHY"" motif is present in two regions and is reported to be involved in the heterodimerization of E1 and E2 and binding with CD81.""
D32.10 binding peptides 292-306, 480-494 and 608-622 were tested for binding of human IgG from HCV infected patients. The epitope was deduced by the binding patterns.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
