Conformational variation between allelic variants of cell-surface ovine prion protein. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Conformational variation between allelic variants of cell-surface ovine prion protein.

Dataset

identifier:	1276711
description:	epitope description:PVDQY antigen name:Major prion protein host organism:Mus musculus PrP null antibody name:683, 884
aggregation:	instance of dataset
availability:	available
primaryPublications:	15070397

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1001444
landingPage:	http://www.iedb.org/assay/1276711

Publication

type:	Literature
publicationVenue:	Biochem J
dates:	2004

Dimension

study type:	b cell assays
subject species:	Ovis aries

Person

fullName:	Alana M Thackray Sujeong Yang Edmond Wong Tim J Fitzmaurice Robert J Morgan-Warren Raymond Bujdoso

Data Type

method:	western blot

Study

name:	Conformational variation between allelic variants of cell-surface ovine prion protein.
description:	The epitope-specific monoclonal antibodies 683 and 884 bound to recombinant versions of allelic variants VRQ and ARQ of PrP (but not ARR); this suggests that the epitope is a common sequence between the two variants.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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